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diagnosis differential neurology causes management anosmia cns complications cord demyelinating disorders erythematosus hearing histiocytosis langerhans lch lupus myelitis pagetsdisease pathophysiology
Tinnitus - Subjective (heard only by patient) - 90% - Differential Diagnosis Algorithm Unilateral On Audiogram -
Differential Diagnosis Algorithm ... • Méniére's Disease ... Causes: Thyroid Dysfunction ... • Whiplash • Skull ... Fracture • Closed
Anosmia / Smell Dysfunction - Differential Diagnosis Algorithm Nasal Obstruction/ URTI: • Septal Deviation • Allergic Rhinitis
Anosmia / Smell Dysfunction ... Surgery • Base of Skull ... Fracture • Nasal ... Fracture Endocrine ... #Loss #Differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
responses - Loss ... compression by fractured ... Sarcoidosis, Behcet disease ... Bowel and bladder dysfunction ... differential #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
super-antigen mediated disease ... Alterations: - Sensory features ... not swollen or less ... Pleocytosis > 100 cells ... MCTD - Bechet disease
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
arthritis, weight loss ... Angioimmunoblastic T-cell ... syndrome Clinical Features ... mild cognitive dysfunction ... : • Chronic B-cell
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
: LCH exhibits features ... commonly in the skull ... • Endocrine Dysfunction ... marrow: Organ dysfunction ... for endocrine dysfunctions
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... -> Pathologic fractures ... radiculopathy • Skull ... causes middle ear dysfunction ... Conductive hearing loss
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM What Are Demyelinating Diseases? • Conditions that damage myelin, the protective
Oligoclonal bands, cell ... Symptoms: Visual loss ... • Features: Bilateral ... unilateral visual loss ... bladder/bowel dysfunction
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