43 results
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
Woltman’s sign on ... reflex — Woltman’s sign ... Woltman’s sign, ... #Woltmans #Signs ... Reflexes #Delayed #Clinical
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... the etiology Signs ... #endocin #endocrinology ... #symptoms #signs ... #diagnosis
Epiglottitis - Swollen inflamed epiglottis 
Clinical (Rapid onset) 
 • Fever 
 • Sore throat
inflamed epiglottis Clinical ... Haemophilus influenzae type ... #Epiglottitis #Signs ... #Causes #Diagnosis ... #Differential #
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
fast-twitching Type ... slow-twitching Type ... fibers Spectrum of Clinical ... #signs #symptoms ... #endocrinology
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in macrophages Diagnosis ... in GBA1 gene Clinical ... Neurological involvement (type ... #Signs #Symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... fractures • Short ... • Obesity -> Type ... Syndrome #genetics #pathophysiology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology ... #pathophysiology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Algorithm and Differential ... Diagnosis Baseline ... investigations depending on clinical ... context and signs ... #Diagnosis #nephrology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... decreased reflexes Pathophysiology ... Residency @CMC_IM #Potts