18 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... Lysosomal storage disorder ... in GBA1 gene Clinical ... Neurological involvement (type ... Disease #Diagnosis #Signs
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... investigations depending on clinical ... context and signs ... renal biopsy • Interstitial
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... fractures • Short ... • Obesity -> Type ... Syndrome #genetics #pathophysiology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
neurocognitive disorders ... workup 1) Clinical ... diagnostic workup What type ... (parkinsonian signs ... MNCD #Dementia #Differential
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
and Headache - Differential ... miosis • Tension-type ... migraine and tension-type ... Traumatic brain injury ... meningeal irritation signs
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Pathogenesis and Clinical ... Findings Compression/injury ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... - Differential ... neurological lesion: Clinical ... • Symptoms and signs ... #algorithm
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
acute ischemic disorder ... thrombosis of short ... Clinical manifestations ... Doppler US : halo sign ... Ophthalmology #Diagnosis #Algorithm
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... or acute kidney injury ... 109 mm Hg) with clinical ... renal bruit or signs ... Neurologic disorders
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
Edema (NCPE) - Differential ... severe with any type ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs