37 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Pathogenesis and clinical ... Signs/Symptoms ... fractures • Short ... • Obesity -> Type
Clinical Features of Infective Endocarditis

General 
 - Malaise 
 - Clubbing 

Cardiac 
 - Murmurs
Clinical Features ... Eyes - Roth spots ... #Endocarditis #Symptoms ... #Signs #Features ... #PhysicalExam #
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Characteristic clinical ... • Brushfield spots ... iris (pigmented spots ... #PhysicalExam # ... Features #Signs
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
(Wallenberg's syndrome ... most common type ... Syndrome usually ... varying neurologic signs ... Vertigo #Causes #differential
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Pathogenesis and Clinical ... Ehlers-Danlos syndrome ... Turner, Marfan syndromes ... Changes in collagen types ... / Symptoms / Complications
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
investigations depending on clinical ... context and signs ... renal biopsy • Interstitial ... Abdominal compartment syndrome ... • Cardio-renal syndrome
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Stevens-Johnson syndrome ... necrolysis, Acute interstitial ... eosinophilia systemic symptoms ... syndrome, Hemolytic ... there is a strong clinical
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... patients with clinically ... stimulation Clinical ... taper 3-7 days - Short
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Wernicke-Korsakoff syndrome ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
Diagnosis and Causes Clinical ... ↑ "Right Sided-Symptoms ... Amyloid, Wild Type ... Hyper-eosinophilc Syndrome ... Diagnosis #Causes #differential