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symptoms management differential clinical msk pathophysiology arthritis syndrome dermatology hematology radiology systemic treatment workup algorithm causes dermatomyositis neurology oncology ophthalmology
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... , Pulmonary Disease ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Cutaneous and Systemic Findings in Dermatomyositis Cutaneous Findings: - Heliotrope sign and edema - Nail-fold changes -
- Heliotrope sign ... or shawl sign ... be tender) - Interstitial ... Dermatomyositis #Diagnosis ... #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
- Signs and Symptoms ... Renal: Tubulo-interstitial ... Arthritis #RA #Signs ... #Symptoms #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
healthy adults, and should ... likely it will be clinically ... • Rheumatic Diseases ... , Interstitial Pulmonary ... #diagnosis #differential
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
hands/feet, knees, shoulders ... Signs & Symptoms ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... Pulmonary: ILD (interstitial ... lung disease), ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... #rheumatology #
Gaucher Disease Pathophsiology • Lysosomal storage disorder • Deficiency of ß-glucocerebrosidase • Accumulation of glucosylceramide in macrophages Diagnosis
Gaucher Disease ... in macrophages Diagnosis ... in GBA1 gene Clinical ... Neurological involvement (type ... #Diagnosis #Signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... like rheumatoid ... erythematosus (SLE) Signs ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... tends to cause interstitial ... lung disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis
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