18 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... Musculoskeletal: joint ... #diagnosis #signs ... #symptoms #testing
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... lesions Abdominal pain ... (20%) Renal disease ... #signs #symptoms ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
should be interpreted ... context of other symptoms ... likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... bacilli to bone/joints ... damage - CXR should
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
Clinical Findings ... mellitus, thyroid disease ... pain • Incr Shoulder ... painShoulder ... #signs #stages
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
axial (spine, shoulders ... noninflammatory Signs ... constitutional symptoms ... arthritis • SLE ... Symmetrical: • RA • SLE
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
Clinical findings ... • Pain in lumbar ... more constant as disease ... #diagnosis #signs ... #symptoms
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Systemic lupus ... Tests for All Types ... RF test should ... low back pain) ... and RF (if clinical
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... • Type-I Interferonopathies ... pain • Swan neck ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... inflammatory lesions-interstitial ... Symptoms (Sx) in ... purpura: strong sign ... SLE) • Urinalysis