9 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
of action on the ... ) 4) Thiazides-type ... Metolazone) 5) Potassium-sparing ... #pharmacology # ... nephrology #medications
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... loop or thiazide diuretics ... blood pressure: Active ... of sodium and potassium ... #nephrology #differential
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
which are short acting ... ) to normalize Potassium ... a contraction metabolic ... Early nephrologv ... Fluid #Balance #management
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Gap Metabolic Acidosis ... Potassium-sparing ... diuretics (amiloride ... aniongap #NonGap #Metabolic ... diagnosis #causes #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... irrigation • Management ... Torsemide) • Acute pulmonary ... the Nonspecific Cation ... #Nephrology #Pharmacology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... vomiting/ nasogastric suction ... syndrome (11-ß HSD type ... other • Severe potassium ... Diagnosis #Causes #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • Recent IV potassium ... infusions) - Metabolic ... Failure • SLE • Type ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• K sparing diuretics ... • Recent IV potassium ... infusions) - Metabolic ... Failure • SLE • Type ... #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Diagnosis and Management ... Aldosterone, RTA Type ... (10g PO tid) - caution ... #Treatment #potassium ... #nephrology #K