18 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... Symptomatic anemia Diagnosis ... if neutropenic fever ... #management #treatment ... #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Summary Diagnostic ... • Treatment algorithms ... #Management #Summary ... #treatment #hematology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Croup Diagnosis and Management Pearls
Common childhood illness, usually viral and self limiting. Characterised by a seal-like
Croup Diagnosis ... and Management Pearls ... hoarse voice +/- fever ... Treatment: Single ... #peds
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - 80% have fever ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... → fevers, night ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
the chest/trunk Symptoms ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology # ... management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
HLH signs and symptoms ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... : >3 symptoms, or ... Renal Failure Treatment ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... aplastic anemia Treatment ... • Improve the symptoms ... #diagnosis #management