14 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
(ALP) Elevation ... Algorithm ALP ... : - Enzymes that ... - Increased ALP ... Intestine - Other causes
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... + ULN ALT) / (alkaline ... Transaminitis #diagnosis ... #differential #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... synthesized in: liver ... Most cases diagnosed ... deficiency • blood ... Phosphatase: • Other causes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
• Elevation of ALP ... Enzyme Elevation ... intestines, White blood ... #chemistry #diagnosis ... #differential #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
the magnitude of enzyme ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... Abnormal #Algorithm #Hepatology ... #Liver #Enzymes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... disease - If ALP ... Enzyme Elevation ... hemolysis) • ALP ... intestines, white blood
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential Diagnosis ... • Pregnancy - AFLP ... Others #LFTs #Hepatology ... #Algorithm #Causes
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... ) Differential Diagnosis ... iMedEducation #AFLP ... Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
enzymes, and Low ... of Pregnancy (AFLP ... obstetrics #hepatitis #comparison ... #differential #diagnosis ... #icp #HELLP #AFLP