37 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... age, however the disease ... following: • Fever ... #management #treatment
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... : Fever, Arthralgia ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Clinical Algorithm for Emergency Department Evaluation and Management of UTI in Febrile Infants and Young Children

Urinary
Clinical Algorithm ... Evaluation and Management ... department with fever ... #Diagnosis #Management ... Febrile #Infant #Peds
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
A subset of hemophagocytic ... is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... Lung Abscess - Clinical ... : • 80% have fever ... Intervention: - Fevers ... #treatment #diagnosis
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
incomplete Kawasaki Disease ... old on day ≥7 of fever ... if they have no clinical ... echo is positive, treatment ... #Diagnosis #Peds
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
disease caused ... Lutzomyia verrucarum Clinical ... Nodular → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... #diagnosis #management
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
with or without treatment ... , but without treatment ... ) ▪ Malaise, fever ... Syphilis #Rash #Diagnosis ... #Clinical #Photo