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hematology chronic cll differential hodgkins lymphocytic lymphoma syndrome algorithm anemia aplastic apml bandemia cancer cbc classification comparison differentiation gangrenosum hemeonc
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... risk-stratification • Risks: infection ... transformation to acute leukemia ... Management • ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... phenomenon CLL Diagnosis ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... involved) • No leukemic ... Etiology: - Infections ... NonHodgkins #comparison #oncology ... #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... right with bands being ... Tissue damage • Leukemia ... likelihood of negative clinical ... neutrophil #WBC #CBC #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... opacities • Diagnosis ... : Infection (sepsis ... #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Pyoderma Gangrenosum (PG) 50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
Diagnosis? ... wide variety of clinical ... Management of PG ... Indiana University Infectious ... #photo #dermatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... median age at diagnosis ... cardiovascular or pulmonary ... may result in an infection ... importance of clinical
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