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differential hematology joint management skin vasculitis activation algorithm apml causes classification conditions dermatologic differentiation extrarticular granulomatosis lesions macrophage mas nonpalpable
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
• Rheumatic fever ... Crohn's disease Palpable ... Sarcoidosis • GPA ... #differential #diagnosis ... #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Red Flags: • Fever ... lesions • Severe pain ... RA, Sjogren's, GPA ... Algorithm #Causes #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... burning sensation or pain ... • Goodpasture syndrome ... #dermatology #rash ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... mountain spotted fever ... #hematology #rheumatology ... #dermatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Wilson's disease Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... #differential #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... mucositis - Rash ... Vasculitis: • Fevers ... scleritis • Palpable ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis: • Fevers ... and branches • Fever ... , mucositis • Rash ... #Rheumatology
Pustular Skin Lesions - Differential Diagnosis Framework What are pustules? • Pustules < 5-10 mm + pus • Material
- Differential Diagnosis ... Generalized itchy rash ... with rheumatic pain ... Pustules + Fever ... #Dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... effusions, weight gain ... Imaging: CXR- pulmonary ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
is the main clinical ... - Nonremitting fever ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
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