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hematology management myelodysplastic rheumatology syndrome algorithm aplastic cancer erythematosus hemeonc hemophagocytic hlh leukemia lupus lymphohistiocytosis macrophage myelodysplasia sle systemic treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bleeding, and petechiae ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Syndrome (MAS) ... manifestation of MAS ... or purpuric rash ... Plasma exchange #MAS ... #Syndrome #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... cytopenias (usually anemia ... #MDS #Diagnosis ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... platelets) • MDS ... precursors MDS ... chemotherapy #MDS ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... lymphopenia, low PLT • Anemia ... (C3 and C4) • ds-DNA ... Chronic B-cell activation ... Erythematosus #Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... Significant ↓ PLT: Petechiae ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... Myelodysplastic syndromes ... median age at diagnosis ... cardiovascular or pulmonary ... disease tolerate anemia
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... (often termed MAS-HLH ... Syndrome) 3. ... - Cytopenias (anemia ... #Management #Hematology
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