22 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Clinical Findings ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... exertion • Neurologic ... neuropathies • Skin ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Serotonin Syndrome • Ophthalmologic ... Cardiovascular and ... Hyperthermia UCSD ... Serotonin #Syndrome #Symptoms ... #diagnosis
What is a Boxer’s fracture?? Fracture of the 4th or 5th metacarpal neck
 - Common in
Symptoms/exam ... ulnar part of hand ... Always check for skin ... Overlying wounds or signs ... #Metacarpal #Diagnosis
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
• Delayed-type skin ... quality - groin and ... Scarlet #fever #diagnosis ... #clinical #photo ... #signs #symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... patients with clinically ... stimulation Clinical ... objective evidence of neurologic ... #management #neurology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... Sporotrichiosis #Infection #clinical ... #photo #hand
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Abdominal Striae, Thin Skin ... the patient's hand ... Cushings #Syndrome #Signs ... BuffaloHump #Striae #Clinical ... #Photo
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... injury) • Neurologic ... Behcet syndrome (Clinical ... inhibitors • Uveitis- Ophthalmology ... #management #signs
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... Syphilis #Rash #Diagnosis ... #Clinical #Photo