22 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... neuropathies • Skin ... dysrhythmias • Ophthalmologic ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Extrapulmonary manifestations of sarcoidosis.
a. Endobronchial cobblestones (a nodular appearance of the tracheal wall mucosa). 
b. Diffuse
earlobe due to skin ... lesions in the hand ... lesion of the skin ... manifestations #clinical ... #photo #diagnosis
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Clinical Findings ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Serotonin Syndrome • Ophthalmologic ... Cardiovascular and ... Hyperthermia UCSD ... Serotonin #Syndrome #Symptoms ... #diagnosis
What is a Boxer’s fracture?? Fracture of the 4th or 5th metacarpal neck
 - Common in
Symptoms/exam ... ulnar part of hand ... Always check for skin ... Overlying wounds or signs ... #Metacarpal #Diagnosis
Scarlet fever
• Delayed-type skin reactivity to pyrogenic exotoxin Requires prior exposure
• Diffuse erythematous eruption that generally
• Delayed-type skin ... quality - groin and ... Scarlet #fever #diagnosis ... #clinical #photo ... #signs #symptoms
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... nodes: 13-15%, skin ... #Diagnosis #Management ... #Signs #Symptoms
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wane; diagnosis ... trauma leads to skin ... painless, no systemic signs ... Sporotrichiosis #Infection #clinical ... #photo #hand
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Abdominal Striae, Thin Skin ... the patient's hand ... Cushings #Syndrome #Signs ... BuffaloHump #Striae #Clinical ... #Photo
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis Diagnosis ... Signs and symptoms ... patients with clinically ... stimulation Clinical ... #management #neurology