35 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... anti-synthetase syndrome ... see mechanics hands ... anti-HMGCR myopathy ... after 2 years of treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... Difficulty raising the arms ... Atorvastatin Diagnosis ... #diagnosis #management ... #treatment
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... What findings are ... the patient's hand ... Next diagnostic
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Occurs on the arms ... papules) on the arms ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
- Differential Diagnosis ... Mitochondrial myopathy ... gravis • Ocular myopathy ... Redundant eyelid skin ... #ophthalmology
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
nodular rash of arm ... wane; diagnosis ... trauma leads to skin ... Infection #clinical #photo ... #hand
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... , but without treatment ... the palms of the hands ... Syphilis #Rash #Diagnosis ... #Clinical #Photo
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... sterile and are ... Irregular pustules on hands ... SAPHO syndrome ( ... Sweet syndrome
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
E2 production and ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... loss from the skin ... Hyperthermia #comparison #diagnosis
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Can begin in arms ... Absent Reflexes: Arms ... Paresthesias: Hands ... Guillain-Barre Diagnosis ... #treatment #neurology