12 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Necrotizing myopathy ... anti-synthetase syndrome ... see mechanics hands ... anti-HMGCR myopathy ... after 2 years of treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... any time during treatment ... • Myalgia • Myositis ... Difficulty raising the arms ... inclusion body myositis
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... gain (license photo ... What findings are ... the patient's hand
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
• HIV related myelopathy ... • Transverse myelitis ... Syringomyelia • Spinal AVM ... stimulation of skin ... T2 Treatment
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... with or without treatment ... , but without treatment ... the palms of the hands ... Diagnosis #Clinical #Photo
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... the spinal cord (Myelopathy ... extensors of the arms ... Oligoclonal IgG bands ... Treatment: •
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
loss, arthralgia, arm ... bruits, asymmetric arm ... Conjunctivitis, mucositis ... occasional oligoclonal bands ... vasculitis • Cogan syndrome
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
macrognathia), ↑ hand ... , hair growth, skin ... tags, skin thickening ... Beckwith Wiedemann syndrome ... Endocrinology #Treatment
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neuritis • Partial myelitis ... • Or brainstem syndromes ... are found in up ... Multiple Sclerosis Treatment ... management #neurology #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... demyelinating disease, myelopathy ... neuropathy, transverse myelitis ... amyloidosis, PAH Skin ... Adenocarcinoma Treatment