14 results
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
CREST Syndrome: ... tightening of skin ... TELANGIECTASIA (In face, hands ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Ophthalmologic ... Cardiovascular and ... Hyperthermia UCSD ... #Symptoms #spectrum ... #signs #diagnosis
What is a Boxer’s fracture?? Fracture of the 4th or 5th metacarpal neck
 - Common in
falls onto the hand ... Symptoms/exam ... ulnar part of hand ... Always check for skin ... – compartment syndrome
Cushing's Syndrome - Moon Facies, Buffalo Hump, Abdominal Striae, Thin Skin

A young man presents with rapid
Cushing's Syndrome ... Abdominal Striae, Thin Skin ... gain (license photo ... the patient's hand ... #Signs #MoonFacies
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Infection #clinical #photo ... #hand
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Behcet disease) Differential ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs ... #symptoms #rheumatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
this disease, and ... Skin rash and malaise ... The signs and symptoms ... the palms of the hands ... Diagnosis #Clinical #Photo
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... occasional oligoclonal bands
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... • Cogan Syndrome ... ear disease Differential ... Presentation - Systemic Symptoms ... purpura: strong sign
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... variably: On one hand ... required due to skip ... required +/- prompt ophthalmology