9 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... develops (DIC, ascites ... AST/ALT (5-10x ULN ... infiltration) Differential ... #Pregnancy #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Wilson's • Pregnancy ... Others #LFTs #Hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... of pregnancy ... #Causes #diagnosis ... #differential # ... hepatology #SAAG
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... AIH, Wilsons, Pregnancy ... #hepatology #LiverFunctionTests
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... of portal HTN: ascites ... of pregnancy ... #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Diagnosis High ... - Massive liver ... - Acute fatty liver ... of pregnancy ... #Diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
• ALP > 1.5 x ULN ... or higher • Liver ... bile ducts Differential ... cholestasis of pregnancy ... #workup #hepatology
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
during pregnancy ... pits <100k), ↑ liver ... enzymes (2x ULN ... hemolysis, elevated liver ... obstetrics #cardiology #differential
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
Pyogenic liver abscess ... #abscess #pediatrics ... #children #peds ... #differential # ... diagnosis #hepatology