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lfts abnormal abscess aflp algorithm biliary chemistry children cholangitis cholestatic cirrhosis elevated enzymes fatty hepatocellular interpretation liverfunctiontests management obgyn obstetrics
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
value = (ALT + ULN ... phosphatase + ULN ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... for Transaminitis ... #hepatology #LiverFunctionTests
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... AST/ALT (5-10x ULN ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... • ALP > 1.5 x ULN ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... #abscess #pediatrics ... #children #peds ... #differential # ... diagnosis #hepatology
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