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hematology causes disorders algorithm bruising obstetrics pregnancy purpura abscess aflp anemia biliary bleeding cardiology children cholangitis cirrhosis comparison dermatology disease
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... #Differential # ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered Platelet ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
in Children Platelet ... - Increased platelet ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
Platelet Disorders - Differential Diagnosis Framework Qualitative Defects: • Adhesion • Aggregation • Secretion Quantitative Defects: • Production:
Platelet Disorders ... - Differential ... • Production: Liver ... #Diagnosis #hematology ... #thrombocytopenia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... with or without platelet ... Schistocytes, thrombocytopenia ... #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... inflammation • Thrombocytopenia ... deficiency • Liver ... #Diagnosis #hematology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
enzymes, and Low Platelets ... features: Hemolysis, Thrombocytopenia ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential ... #diagnosis #icp
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... intravascular hemolysis Platelet ... and decreased platelet ... WBC count and differential ... #Workup #Hematology
Hypertensive Disorders of Pregnancy Chronic Hypertension: • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg •
organ injury: thrombocytopenia ... pits <100k), ↑ liver ... enzymes (2x ULN ... enzymes, Low platelets ... obstetrics #cardiology #differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... • ALP > 1.5 x ULN ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
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