3147 results
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Hepatitis (eg Viral) Management ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... AIH #Diagnosis #Management ... #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
AST/ALT (5-10x ULN ... Intrahepatic Cholestasis Management ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Biliary Cirrhosis - Management ... if ALP > 1.5x ULN ... Non-pharmacological management ... non-pharmacological management ... #Treatment #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
IU/mL and ALT > ULN ... #Indications #management ... #hepatology
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
Diagnosis and Management ... 50mg/dL, LDH > ULN ... Ascites #Diagnosis #Management ... #Summary #Hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Phosphatase, ALT ≥ 3x ULN ... Transaminase, ALP ≥ 2x ULN ... Value = (ALT / ULN ... ALT) / (ALP / ULN ... Transaminitis #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Severe ALT > 15x ULN ... Moderate ALT 5-15x ULN ... Mild ALT < 5x ULN ... Others #LFTs #Hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
value = (ALT + ULN ... phosphatase + ULN ... #differential #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN ... Algorithm #diagnosis #hepatology
Radius and Ulna Anatomy

By @rev.med

#Radius #Ulna #Anatomy #Bones #orthopedics #MSK
Radius and Ulna ... rev.med #Radius #Ulna