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diagnosis hematology algorithm causes management anemia pathophysiology workup treatment cirrhosis gastroenterology hepatic thrombocytopenia classification comparison table lfts oncology ascites disease
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... value = (ALT + ULN ... phosphatase + ULN ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Severe ALT > 15x ULN ... Others #LFTs #Hepatology ... #LiverEnzymes #Differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Mild - ALT < 5x ULN ... Algorithm #diagnosis #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... AST/ALT (5-10x ULN ... infiltration) Differential ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... • ALP > 1.5 x ULN ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... specific for the liver ... Value = (ALT / ULN ... SinaiBmoreIMRes #Liver ... Transaminitis #diagnosis #hepatology
Table of Causes of Acute Liver Injury #Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Causes of Acute Liver ... Injury #Diagnosis #Hepatology ... #Acute #Liver # ... Injury #Causes #Differential
Liver Mass Differential Diagnosis Solid: • Benign: Hepatic Hemangioma, Focal nodular hyperplasia, Hepatocellular adenoma, Regenerative nodules •
Liver Mass Differential ... Cystadenoma, Polycystic liver ... Echinococcus #Liver ... #Mass #Differential ... #Diagnosis #hepatology
Causes of Granulomatous Liver Diseases - Differential Diagnosis Infections (Bacterial, Viral, Fungal, Parasitic) Malignancy Autoimmune Drugs/Toxins Others #Granulomatous #Liver #hepatic #granulomas #Differential
Granulomatous Liver ... Diseases - Differential ... Granulomatous #Liver ... hepatic #granulomas #Differential ... #Diagnosis #hepatology
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