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diagnosis differential clinical hepatology management algorithm pocus causes ultrasound hematology treatment pathophysiology radiology hepatic gastroenterology cirrhosis photo physicalexam disease comparison
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... or Cholestatic Liver ... @AnnKumfer #Liver
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... kidney, brain ALT ... specific for the liver ... / ULN ALT) / (ALP ... SinaiBmoreIMRes #Liver
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... /ULN ALT) / (Alk ... Identify Acute Liver ... than ALT • ALT ... : Specific to liver
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... : • Severe - ALT ... >15X ULN ... • Moderate - ALT ... < 5x ULN
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ALT ... > 15x ULN • Viral ... HELLP Moderate ALT ... • Others Mild ALT
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... Findings: • ↑AST/ALT ... (5-10x ULN), ↑Tbili ... Cr, ↓Glucose, ↓PLT
Features of Components of Liver Function Tests #Diagnosis #IM #GI #LFTs #Liver #Function #Tests #Locations #AlkPhos
Components of Liver ... #IM #GI #LFTs #Liver ... #AlkPhos #AST #ALT
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... Vitals - LFTs, plt ... MELD - Chronic liver ... disease work up - Liver ... US - Prior liver
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Liver Function Tests ... aminotransferase (ALT ... Prothrombin #Liver
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
than ALT • ALT ... elevated ALP • AST/ALT ... • AST: ↑ • ALT ... - ALP > AST/ALT ... kidney, brain • ALT
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