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hyponatremia differential cancer comparison hypotonic low oncology pathophysiology physiologic saltwasting table volume
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Cerebral Salt Wasting ... Neurological event 2) Sodium ... reabsorption 5) ↓ Na ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
- RAAS ON (UNa ... > 30): SIADH, Medications ... Reset osmostat, Cerebral ... #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... , Renal Sodium loss ... Insufficiency, Cerebral ... #differential #diagnosis ... #nephrology
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Renal losses, Cerebral ... uric acid <4 • SIADH ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential Diagnosis ... Algorithm in Cancer ... inappropriate • SIAD ... tumors, brain or lung ... #nephrology #oncology
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