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hyponatremia differential causes cerebral hypotonic pathophysiology physiologic saltwasting table
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine ... can be high or low ... intake, UNa <20 ... #differential #diagnosis ... #nephrology
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
uric acid <4 • SIADH ... Hypothyroidism, Low ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Neurological event 2) Sodium ... reabsorption 5) ↓ Na ... Pathophysiology #diagnosis ... #nephrology #hyponatremia ... #comparison
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
> 30): SIADH, Medications ... Primary polydipsia, Low ... solute intake, ... #diagnosis #sodium ... #nephrology
Hyponatremia Diagnosis Algorithm UOsm ≥ POsm - Vasopressin-Dependent • UNa < 20 mEq/L - Appropriate (↓ EABV)
Algorithm UOsm ... Inappropriate - Consider: SIADH ... Primary polydipsia, Low ... solute intake, ... #causes #nephrology
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