7 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... → ADH → water reabsorption ... 5) ↓ Na+ → Subclinical ... Pathophysiology #diagnosis #nephrology ... #hyponatremia #
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
< 30): Hypovolemia ... > 30): SIADH, Medications ... Reset osmostat, Cerebral ... Algorithm #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
or Ineffective (UNa ... (Uosm ≥100): SIADH ... , Renal Sodium loss ... Insufficiency, Cerebral ... #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Hypovolemic, Serum ... Renal losses, Cerebral ... uric acid <4 • SIADH ... algorithm #diagnosis #sodium ... #low #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... promoting passive sodium ... antagonists: • Blocks ADH ... #Management #hyponatremia ... #nephrology #treatment
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
consequence of cerebral ... hypervolemic, hypovolemic ... #hyponatremia #ADH ... #RAAS #Hypovolemia ... EBV #potomania #SIADH
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... promoting passive sodium ... vaptans) • Blocks ADH ... #Management #hyponatremia ... #nephrology #treatment