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nephrology algorithm differential management table cancer causes cerebral comparison criticalcare ebv hyperacute hypotonic hypoxemia hypoxia low oncology osmolality pathophysiology physiologic
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
or Ineffective (UNa ... (Uosm ≥100): SIADH ... , Renal Sodium loss ... #differential #diagnosis ... #table #sodium
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
: • ADH ON (UOsm ... < 30): Hypovolemia ... > 30): SIADH, Medications ... #Algorithm #diagnosis ... #sodium #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Neurological event 2) Sodium ... → ADH → water reabsorption ... 5) ↓ Na+ → Subclinical ... Pathophysiology #diagnosis ... #nephrology #hyponatremia
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... Hypovolemic - Give ... • UOsm > 300 - ADH ... , SSRIs) - SIADH ... #nephrology #sodium
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
pain, primary lung ... promoting passive sodium ... osmolality < 538 AND UNa ... antagonists: • Blocks ADH ... #nephrology #treatment
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
hypervolemic, hypovolemic ... #hyponatremia #ADH ... #RAAS #Hypovolemia ... EBV #potomania #SIADH ... #Thiazides #UNAa
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
Hyponatremia - Differential ... Diagnosis by Mechanism ... secretion (SIADH ... carcinoma of the lung ... Table #Causes #Sodium
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Based Approach to Hyponatremia ... Hypovolemic, Serum ... uric acid <4 • SIADH ... #algorithm #diagnosis ... #sodium #low #nephrology
SIADH Treatment Options 1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
SIADH Treatment ... Pain, Primary lung ... promoting passive sodium ... vaptans) • Blocks ADH ... #Management #hyponatremia
Management of Hyponatremia Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125 Give
Management of Hyponatremia ... Normalizes in SIADH ... • IF SIADH — ... give specific treatment ... #sodium
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