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diagnosis differential management oncology thrombocytosis algorithm crisis gap globulin mds myelodysplastic nephrology protein proteingap renal scleroderma secondary src syndrome treatment
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... malignancies • Anemia ... Chronic myeloid leukemia ... #hematology #secondary
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Management #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... ALL (Acute Lymphoblastic ... -> AML: Blast crises ... - infiltrates (anemia ... #Hematology #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gastric tumors • Hematology ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia ... inflammation (acute ... differential #diagnosis #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Renal Crisis: 1) Acute ... microangiopathic hemolytic anemia ... , add other BP meds ... • Refractory cases ... Renal #Crisis #rheumatology
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