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management differential anemia classification hemophagocytic hlh lymphohistiocytosis oncology agglutinin aplastic bilateral cd4 cell cold common cryoglobulinemia cryoglobulins cvid disease erythematosus
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
in case of Pneumonia ... travel hx, home meds ... Progressive URI ... NOT definitively diagnose ... #clinical #ultrasound
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 Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
NEJM 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
originate from a low-grade ... Viral infection, autoimmune ... Viral Infection Clinical ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... solid cancers • Autoimmune ... Drugs, Unknown cause ... treatment #summary #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... : Pneumonia • Autoimmune ... thrombocytopenia and autoimmune ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... Labs/Diagnosis: ... classification #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... may result from low ... Anemia #oncology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... disease • Non-autoimmune ... rheumatologic diseases ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
acute HIV, HBV, EBV ... Cirrhosis, ETOH, autoimmune ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
ASSOCIATIONS W/ LOW ... CD4 • Autoimmune ... EBV. CMV. ... #hematology #Differential ... #Causes #lymphocytopenia
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