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diagnosis management lupus erythematosus summary systemic acidosis bilateral blines cardiology cardiomyopathy cerebritis classification cns comparison derm differential druginduced elevation granuloma
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... : SLE+++, Adult-onset ... Still disease, ... Treatment: • ... #summary #rheumatology
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
Bilateral B-Lines in case ... travel hx, home meds ... Progressive URI ... interstitial lung disease ... #clinical #ultrasound
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 Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... presentations and disease ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... orthopnea, PND, LE ... teratogenic GDMT meds ... management #cardiology #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
sawtooth rete pegs ... an autoimmune disease ... used in primary treatment ... #NEJM #clinical ... #photo #lichen #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... as: • SLE • RA ... Diagnosis: • Clinical ... affected tissue Treatment ... Polychondritis #rheumatology
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