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diagnosis management hematology classification injury kidney neurology acidosis behcets bloodsmear borrelia clinical differential disease elevation encephalopathy gravis hemophilia lactate lactic
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
a.k.a. cardiorenal syndrome ... a.k.a. hepatorenal syndrome ... tubular necrosis (causes ... : sepsis, meds, ... prolonged prerenal AKI
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... (AKI) - Management ... • Hepatorenal syndrome ... long-term Foley • UTI ... Medications → Stop meds
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... transformation to acute ... only curative treatment ... #hematology #oncology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... organ damage • Treatment ... diagnosis #management #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... muscles: “myasthenic crises ... Myasthenia Crises ... aspiration and acute ... immunosuppressants - Meds
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... - Acute Bleeding ... by a hemophilia treatment ... Avoid meds that ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
, ADEM, Acute toxic ... epilepticus Treatment ... the underlying cause ... • Treatment of ... until cause identified
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
/ hypoxemia -> focus ... before beginning treatment ... cardiac output - Acute ... - Compartment syndrome ... peritonitis - Acute
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Pediculus humanus, AKA ... Syndrome: 3d of ... of blood smear, acute ... often experience acute ... initiation of treatment
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