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diagnosis signs sle complications management degenerative druginduced erythematosus inflammatory jointdisease jointpain manifestations mucocutaneous musculoskeletal rheumatology sarcoidosis systemic table versus
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... > Mouth, Nasal Ulcers ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Constitutional symptoms ... constitutional symptoms ... Alopecia, oral ulcers ... #sle #comparison
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Rheumatoid arthritis, Lupus ... #Degenerative #Comparison ... #Versus #MSK #JointDisease ... JointPain #Diagnosis #pathophysiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... Features: • Many symptoms ... patients have no symptoms ... skin (16-32%): lupus ... anterior/posterior MSK
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