35 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Summary • Epidemiology ... • Immunologic Workup ... #Management #Summary ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... rare, Malar rash is ... • Immunologic Workup ... constitutional symptoms ... #diagnosis #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... #Summary #diagnosis ... #rheumatology # ... management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... pain • Swan neck/Ulnar ... : • Symptoms limited ... Chronic B-cell activation
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Management Summary ... IBS is NOT a diagnosis ... Symptoms: - ... Gastroenterology and Hepatology ... #Management #gastroenterology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
pattern and titer is ... context of other symptoms ... erythematosus (SLE ... ANA #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... SJIA], systemic lupus ... erythematosus [SLE ... #Syndrome #Diagnosis ... #Management #Hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Workup Summary ... IBS is NOT a diagnosis ... last 3 months + symptom ... Gastroenterology and Hepatology ... #workup #gastroenterology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... Autoimmune diseases: SLE ... #management #treatment ... #summary #rheumatology