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lupus ana systemic differential disease patterns table workup arthritis autoantibodies comparison druginduced igg4 phenotypes related rheumatic sjogrens summary syndrome testing
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
and Associated Rheumatic ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... and fever) and laboratory ... ANCA-associated vasculitis, rheumatoid ... pain • Swan neck/Ulnar ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... versus DIL • Laboratory ... #Diagnosis #Management ... #Summary #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... is clinically suspected ... Lupusreference #Antinuclear ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... (SLE) - Antinuclear ... double-stranded DNA antibodies ... ANA and RF (if clinical
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... relapse No specific laboratory ... autoantibodies (antinuclear ... antibodies, rheumatoid ... #management #phenotypes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... calcium-b) • Laboratory ... Systemic Lupus Erythematosus ... comparison #table #rheumatology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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