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diagnosis nephrology algorithm causes potassium low alkalosis metabolic management urine
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #Syndrome #Pathophysiology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... ratio 0.5%) Differential ... • Congenital chloride ... #nephrology #management ... #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... secreting tumor, Primary ... , Gitelman syndrom ... #Differential # ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... starts by measuring urinary ... , Gitelman's syndrome ... #differential # ... algorithm #causes #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
mEq/g suggests urinary ... ↑ Aldosterone: Primary ... , Gitelman syndrome ... diagnosis #Algorithm #differential ... #potassium #nephrology
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... High Al, Low R - Primary ... , Gitelman's syndrome ... #Hypokalemia # ... #Algorithm #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis - Urinary ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... #Algorithm #nephrology ... #differential #
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Metabolic Alkalosis: Differential ... > 20 meq/L • Primary ... furosemide-like lesion) • Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Causes #nephrology
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
thiazide-like diuretics), Primary ... diuretic use), Gitelman's ... syndrome (mimics ... #Causes #differential ... #diagnosis #nephrology
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