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growthhormone riskfactors acromegaly anorexianervosa bulimianervosa cholesteatoma complications excess feedbackloop hyperparathyroidism management middleear overproduction pituitary primary pth ra rheumatoidarthritis tertiary treatment
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology ... #pathophysiology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
: Commonly no signs ... Bone/joint pain Psychiatric ... Hyperparathyroidism #diagnosis ... #endocrinology ... #Tertiary #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... Acromegaly occurs secondary ... #Management #Endocrinology ... #Treatment #Pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
boggy" joints, esp carpal ... Boutonniere's ulnar ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis
Cholesteatoma (of middle ear): Pathogenesis and clinical findings • Congenital trapping of keratinizing epithelium in middle
external auditory canal ... • Aural Polyp secondary ... Cholesteatoma #MiddleEar #pathophysiology ... #symptoms #signs ... #diagnosis #complications
Anorexia Nervosa: Pathogenesis and Risk Factors Biological Risk Factors • Gender: F > M • Genetics: concordance
having a small waist ... AnorexiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
Bulimia Nervosa: Pathogenesis and Risk Factors Biological Risk Factors • Gender: F > M • Genetics: Some
having a small waist ... BulimiaNervosa #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
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