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Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice Unconjugated ... eg, spirochetal infections ... , infectious mononucleosis ... #unconjugated # ... differential #causes
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias - Differential ... • ↑ Indirect / unconjugated ... Hypersplenism, Infection ... Hemolytic #Anemias #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Internal (RBC) - Infections ... Reticulocyte Count ↑ - Unconjugated ... #Hemolysis #Differential
Algorithm and Differential Diagnosis of Hyperbilirubinemia Direct = Conjugated Indirect = Unconjugated #Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Algorithm and Differential ... Indirect = Unconjugated ... Hyperbilirubinemia #Differential ... Direct #Indirect #Conjugated ... #Unconjugated #
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Workup #Evaluation #Differential ... Direct #Indirect #Conjugated ... #Unconjugated #
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic #Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated ** GrepMed Recommended
#Diagnosis #Differential ... #Extrahepatic #Unconjugated ... #Conjugated
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
Pathophysiology • Conjugated ... Bilirubin • Unconjugated
Liver Function Tests (LFTs) - Aspartate aminotransferase (AST) - Alanine aminotransferase (ALT) - Alkaline
Bilirubin - Unconjugated ... Indirect) - Conjugated
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Liver Injury: • Infectious ... injury: ~ 1 Unconjugated ... injury #hepatitis #differential
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
→ Biliverdin → Unconjugated ... Conjugation → Conjugated ... common bile duct Unconjugated ... bilirubin, and conjugated
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