213 results
Liver Function Tests (LFTs)
 - Aspartate aminotransferase (AST) 
 - Alanine aminotransferase (ALT) 
 - Alkaline
Bilirubin - Unconjugated ... Indirect) - Conjugated ... Laboratory #Diagnosis #Testing
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice Unconjugated ... Crigler-Najjar syndrome ... Dubin-Johnson syndrome ... , Rotor syndrome ... #unconjugated #
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Pre-Hepatic - Unconjugated ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... II) Hepatic - Conjugated
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... Reticulocytes Unconjugated ... Anemia #Laboratory #Testing
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Conjugation == Gilbert Syndrome ... hyperbilirubinemia syndrome ... , intermittent unconjugated ... UGT1A1 activity • Unconjugated ... and unconjugated
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Failure - Elevated conjugated ... and unconjugated ... gluconeogenesis in the fasting ... the hepatorenal syndrome ... Laboratory #Diagnosis #Testing
Hyperthermia Syndromes Comparison
Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia
Cause - Onset - Vitals
Hyperthermia Syndromes ... Comparison Serotonin ... Syndrome - NMS ... #Hyperthermia #Syndromes ... #Comparison #diagnosis
Hyperthermic Syndromes - This table summarizes the similarities and differences between some toxicologic causes of hyperthermic
Hyperthermic Syndromes ... of hyperthermic syndromes ... • Serotonin syndrome ... #Hyperthermic #Syndromes ... #Comparison #Table
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Monoclonal Gammopathy Testing ... Monoclonal #Gammopathy #Testing ... Nephrology #Laboratory #Comparison
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory Syndrome ... Positive COVID testin ... MISC #Kawasaki #Comparison ... #Inflammatory #Syndrome