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diagnosis management differential algorithm gastroenterology injury transaminitis cirrhosis dili aclf acute aih autoimmune blastomycosis calling chemistry classification consultation drug druginduced
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Elevated Liver Function ... Tests (LFTs) - ... Cirrhosis • Chronic ... Function #Tests #LFTs ... Differential #Diagnosis #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
The Liver Consult ... Focus on prior Liver ... - Vitals - LFTs ... current MELD - Chronic ... Calling #Referral #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... #ACLF #Acute #Chronic ... #Cirrhosis #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
presentation • Chronic ... - ongoing ↑ LFTs ... or symptoms of liver ... Drug #induced #Liver ... gastroenterology #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 5-10x normal - Chronic ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology ... transaminitis #LFTs
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
HAV immunity; Liver ... elastographv, liver ... • Liver is the ... Diagnosis #Management #Treatment ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... non-essential drug/HDS treatments ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... Diagnosis #Algorithm #hepatology
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... portosystemic shunting ... noxious stimuli) TREATMENT ... Initiate empiric treatment ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... - Symptoms of chronic ... hepatocellular pattern of liver ... regarding need for treatment ... Diagnosis #Management #Hepatology
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