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diagnosis differential management hematology hepatology classification criticalcare oncology shock ascites aub blanching bruise coagulation common cvid dic disseminated ecchymosis enzymes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... crises • Blasts ... night sweats, bleeding ... • Significant bleeding ... Intracellular Urate
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... Infiltration: Often breast ... function may be abnormal ... RBC (hemolysis, bleeding
ED Treatment of Abnormal Uterine Bleeding Hemodynamically unstable Resuscitation • ABCs! • Fluids +
Uterine Bleeding ... pregnancy related cause ... thromboembolic disease, breast ... cancer, liver dysfunction ... endometrial path0100' or breast
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Coagulation (DIC) Overview ... Schistocytes, helmet cells ... DIC • Severe Liver ... Treatment: • Treat ... primary cause
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... rapidly progresses: cell ... wet (dependent areas ... AI, thyroid dz liver ... #differential #causes
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... Areas of diagnostic ... well include extrahepatic ... #Algorithm #Hepatology
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... rapidly progresses: cell ... wet (dependent areas ... AI, thyroid dz liver ... #differential #causes
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
red, discrete areas ... occur in dependent areas ... follow dependent areas ... ecchymosis) is caused ... in endothelial cells
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... disease • Liver ... - gastric and breast ... levels are within normal ... DDX - Other causes
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... an underlying cause ... : neuro, heme (bleeding ... about secondary causes ... Differential #Diagnosis #Algorithm
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