8 results
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
into contiguous areas ... postauricular crease ... #Mastoiditis #pathophysiology ... #signs #symptoms ... #diagnosis #otology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
white or yellow areas ... around atrophic areas ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Age Related Macular Degeneration: Pathogenesis and clinical findings

Photoreceptor atrophy 
-> Extracellular debris (drusen) from RPE atrophy/metabolism
photoreceptors -> Break ... fundoscopy -> New abnormal ... RPE -> Loss of photo ... MacularDegeneration #pathophysiology ... #ophthalmology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... suspicious clinical symptoms ... Areas of diagnostic ... #Algorithm #Hepatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
in sun exposed areas ... keratinocytes but abnormal ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... damage • Induce blast ... Diagnosis: >3 symptoms ... 500 mg QD until normal ... management #hematology #oncology
Melanoma tumour progression (based on the Clark model)
 - Benign melanocytic nevi: controlled proliferation of normal
proliferation of normal ... dysplastic nevi: abnormal ... spread to other areas ... #Pathophysiology ... #Oncology #Melanoma
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
on the skin • Areas ... Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... - Core temp normal