7 results
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer #EBM #Honc #Alectinib #Crizotinib #ALK #ALKPositive #NSCLC
Crizotinib in Untreated ALK-Positive ... Non–Small-Cell Lung Cancer #EBM ... #Honc #Alectinib ... #Crizotinib #ALK ... VisualAbstract #NEJM
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
/Lymphoblastic Lymphoma ... disease with limited BM ... lauraebrown #BCell #ALL ... Lymphoblastic #Leukemia #Lymphoma ... #hemepath #pathology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
HBV, HCV, HEV, EBV ... Infiltration: Often breast ... cell lung CA, lymphoma ... to liver than ALT ... • AST/ALT > ALP
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
cells - Blood & BM ... • Cytopenia -> BM ... Intracellular Urate ... and secondary lymphoid ... of large cell lymphoma
Anaplastic large cell lymphoma, ALK+
Clinical
 • First 3 decades of life, M>F
 • Often nodal +
Anaplastic large cell lymphoma ... , ALK+ Clinical ... lungs, liver) • BM ... Anaplastic #largecell #lymphoma ... ALKPos #hemepath #pathology
Hepatosplenic T-cell lymphoma involving hepatic sinusoids.

HSTL also involves BM sinusoids and splenic red pulp cords and
Hepatosplenic T-cell lymphoma ... also involves BM ... in essentially all ... Hepatosplenic #TCell #Lymphoma ... #HSTCL #Pathology
Perirenal Extramedullary Hematopoiesis - Magnetic resonance imaging of the abdomen, performed without the administration of contrast
hemosiderin deposition, all ... cilnical #Radiology #Pathology ... #Honc #MRI #PerirenalExtramedullaryHematopoiesis ... ExtramedullaryHematopoiesis #Microscopy #NEJM