21 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... less than 200 cells ... enhancement on CT ... periventricular areas ... effect/Edema • EBV
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... involvement • 30%: CNS ... pain, bleeding, infections ... leukostasis syndrome: CNS ... Intracellular Urate
Lymphadenopathy - Differential Diagnosis Algorithm
Localized: 
 • Cervical: EBV, CMV, HIV, Toxo, TB, Lymphoma, Head /
• Cervical: EBV ... scratch, Tularemia), Breast ... , Sjögren's • Infection ... : Acute HIV, EBV ... Angioimmunoblastic T-cell
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... - Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... - Mycoplasma, EBV
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Diagnosis • Infectious ... HAV, HCV, HEV, EBV ... Infiltration- often breast ... CA, small cell
Decompression Sickness - The physical examination revealed diffuse violaceous skin mottling over his trunk and arms
and vomiting as well ... Clinical #Derm #EM ... #Pneumatosis #CT ... #NEJM
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... history of recurrent infections ... disease • Infectious ... - gastric and breast ... Chest CT: • Ground-glass
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... early stages of infection ... invades mononuclear cells ... in the CNS ○ ... Infected cells -
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... suspected) - CT ... chest; CT abdomen ... abdominal pain; full infectious ... “big & sticky” cells
Radiation Injury
Acute Radiation Toxicity primarily affects rapidly dividing cells based on dosage
Hematopoiteic - Pancytopenia, Infection
 •
rapidly dividing cells ... Pancytopenia, Infection ... Hours Cardio/CNS ... Circuatory collapse, CNS ... - MH/CCF/CWRU EM