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diagnosis differential alkalosis causes metabolic hypokalemia hyponatremia potassium urine aids associated dementia disorder hand hiv hypernatremia hypochloremia hypotonic icucard management
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... alkalosis - Volume ... #Syndrome #Pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Volume Depleted ... , Gitelman Syndrome ... Volume Expanded ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Primary Metabolic ... Volume Depleted ... , Gitelman Syndrome ... Volume Expanded ... #Nephrology #Causes
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Metabolic Alkalosis - Urinary ... Chloride Algorithm ... alkalosis • Normal/low ... , Gitelman syndrome ... #Algorithm #nephrology
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Volume Based Approach ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... secreting tumor, Primary ... , Gitelman syndrom ... Differential #Diagnosis #Algorithm ... #nephrology
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... - Urinary Chloride ... - Normal/low ... , Gitelman syndrome ... #causes #urinary
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Gitelman's syndrome ... alkalosis • Normal or low ... #nephrology #management ... #pathophysiology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Diagnosis ECF volume ... adenomas ECF volume ... > 20 meq/L • Primary ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine ... can be high or low ... Cirrhosis, Nephrotic syndrome ... water intake (Primary ... #nephrology
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