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diagnosis differential alkalosis bartter hypokalemia metabolic aids associated causes dementia disorder epithelial fanconi hand hiv hypochloremia inherited kidney liddle localization
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... • Urine Chloride ... krithicism #Gitelman ... #Algorithm #nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Renal Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Pathophysiology ... #Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Algorithm Cl- ... , Gitelman syndrome ... the excretion of sodium ... #urine #Algorithm ... #nephrology #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... • Gitelman's syndrome ... #nephrology #management ... #pathophysiology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... #Kidney #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
contracted: urine chloride ... expanded: urine chloride ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Differential Diagnosis Algorithm ... - Bartter - Gitelman ... • Fatigue Chloride ... #Pathophysiology ... #Nephrology #Chloride
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... barrier (BBB), and infects ... volume • Patchy areas ... The clinical syndrome ... dementia #AIDS #Neurology
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