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diagnosis differential aids alkalosis associated chloride dementia disorder epithelial fanconi hand hiv hypokalemia inherited kidney liddle localization management metabolic neurocognitive
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Renal Tubular Defects ... Proximal tubule Bartter ... #Nephron #Defects ... #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects ... acid transporter Bartter ... ascending limb Gitelman ... of epithelial sodium ... #Kidney #Nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Urinary Chloride Algorithm ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia ... #nephrology #differential
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... the blood-brain barrier ... (BBB), and infects ... the blood-brain barrier ... The clinical syndrome
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