7 results
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
and Pathophysiology ... 1) Na/K ATPase ... Pump - Digoxin works ... increase. 2) The ... #Pharmacology #Pathophysiology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... renal mechanism 2) ... #Algorithm #nephrology ... #sodium
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Step 1 . ... Repeat the sodium ... Step 2. ... • nephrotic syndrome ... #Algorithm #Nephrology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... precipitates with calcium ... to Manifest: 1. ... Hyperuricemia 2. ... • Metabolic syndrome
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Tumor Lysis Syndrome ... Resistance • Beta-2 ... antagonism • alpha-1 ... agonism • Digoxin ... IntercellularShift #Nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
• Prevalence: 1- ... associated with DM-1, ... Pathophysiology ... antibody that works ... others (botox, sodium
#ICUCard
RENAL
GFR
90-131
mL/min
((140-age)*Wt)/(72*Cr)
Glomerular Filtration Rate (Cockcroft)
CI Cr
90-131
mL/min
(CrU * volume)/CrS
Creatinine Clearance
FENa
0.0-1.0
%
((U/P Na)/(U/P Cr))*100
Fractional Excretion of Na+
Na req
mEq
(125-Na)*0.6*Wt
Required Sodium
FE Urea
0.6*Wt Required Sodium ... FE Urea 20-70 ... Distress Syndrome ... 2min Calcium chloride ... q10min (as needed) Digoxin