14 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Gitelman syndrome ... from Bartter syndrome ... • Urine Chloride ... #syndrome #Bartter ... #Algorithm #nephrology
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Proximal tubule Bartter ... tubule #Liddle ... #Bartter #Gitelman ... Nephron #Defects #Pathophysiology ... #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... , Liddle syndrome ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Low Aldosterone: Liddle's ... thiazide diuretics, Bartter ... syndrome, Gitelman ... potassium #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... , Liddle syndrome ... #Nephrology #Causes
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... diuretic use, Bartter ... syndrome, Gitelman ... #urine #Algorithm ... #nephrology #differential
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
contracted: urine chloride ... deficiency • Liddle ... actively working • Bartter ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Differential Diagnosis Algorithm ... glycyrrhizic acid, Liddle's ... h - Diuretics, Bartter's ... syndrome, Gitelman's ... #nephrology #causes
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Diuresis - Bartter ... - Gitelman ... #Pathophysiology ... #Nephrology #Chloride