16 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Proximal tubule Bartter ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... loss (Diarrhea) Renal ... thiazide diuretics, Bartter ... syndrome, Gitelman ... potassium #low #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #nephrology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Differential Diagnosis Algorithm ... oral intake Renal ... tubular acidosis • Gitelman's ... syndromeBartter's ... #Causes #Classification
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... Epithelial Cells Renal ... acid transporter Bartter ... ascending limb Gitelman ... #Nephrology #Diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... suggests extra-renal ... Emesis, Diuretics, Bartter ... syndrome, Gitelman ... differential #potassium #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... hypokalemia • Renal ... • Diuretics, Bartter's ... syndrome, Gitelman's ... #causes #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Diuresis - Bartter ... - Gitelman ... unloading • Kidney ... #Pathophysiology ... #Nephrology #Chloride
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #nephrology #management ... #pathophysiology